Having "speak" first will break "speak to" and "speak with" - because Quest will parse "speak to character" with a verb of "speak" and an object called "to character".
So, put the more general verb last. Add the verb under Game/Verbs like this:
speak to; speak with; speak; talk to; talk with; talk
Then when adding the verb to an object, don't use the built-in "speak" verb. Add your new "speak to" verb instead.